黄守杰

一 基本情况

黄守杰(Shou-Jie Huang)  男 高级工程师 硕士生导师

中国民主同盟会会员。

二 学习经历

2008年 获厦门大学生物化学与分子生物学硕士学位

1999年 获北京大学公共卫生学院医学学士学位

三 工作经历

2015年 厦门大学公共卫生学院 高级工程师

2012年 厦门大学公共卫生学院 高级实验师

2011年 厦门大学公共卫生学院 实验师

2004年 厦门大学医学院 实验师

1999年 厦门大学医学院 助理实验师

四 主要研究方向

疫苗临床试验、传染病流行病学

五 科研

2006年至今从事疫苗临床试验和传染病流行病学研究,在疫苗临床试验领域具有丰富的经验。作为主要研究成员研究开发了戊型肝炎疫苗、HPV两价疫苗、HPV九价疫苗、7D水痘疱疹疫苗。其中戊型肝炎疫苗属于国家一类新药,2012年成为世界上首个成功上市的戊肝疫苗;HPV两价疫苗预计于2019年年底上市,将成为国内首个上市的宫颈癌疫苗。主持或参与国家自然科学基金、国家传染病重大科技专项(863项目)等10多个项目。已在NEJMLancetHepatologyIJCCMI等国际学术刊物发表论文49篇。先后获得江苏省科学技术奖一等奖(2012年)、求是科技基金会杰出科技成就集体奖(2015年)等科研奖励。

代表性论文

1) Zhiping Chen#, Shuzhen Lin#, Jiafu Duan#, Yan Luo, Shenyu Wang, Zhengkai Gan, Huaiming Yi, Ting Wu, Shoujie Huang*, Qiufen Zhang*, Huakun Lv*. Immunogenicity and safety of an accelerated hepatitis E vaccination schedule in healthy adults: a randomized, controlled, open-label, phase IV trial[J]. Clinical Microbiology and Infection, 2019. (共同通讯,IF: 6.425, JCR: 2区)

2) Yingying Su#, Shoujie Huang#, Meng Guo, Jun Zhao, Huan Yu, Wengang He, Hanmin Jiang, Yijun Wang, Xuefeng Zhang, Jiaping Cai, Changlin Yang, Zhongze Wang, Fengcai Zhu, Dr. Ting Wu*, Jun Zhang, Prof. *, NingShao Xia. Persistence of antibodies acquired by natural hepatitis E virus infection and the effects of vaccination [J]. Clinical Microbiology and Infection, 2017, 23 (5): 336.e1-336.e4. (Co-First Author,IF: 6.425, JCR: 2区)

3) Shou-Jie Huang, Xiao-Hui Liu, Jun Zhang, Mun-Hon Ng*. Protective immunity against HEV [J]. Current opinion in virology, 2014, 5(1): 1-6. (IF: 5.4)

4) H. JIANG#S. HUANG#,Y. ZHAO#,Y. WANG,C. YANG,J. CAI,Z. WANG,J. ZHANG,X. ZHANG*,H. JIN. Disease burden of hepatitis E in a rural population in China: a community-based survey [J]. Epidemiol. Infect., 2017, 145(5): 908-913. (Co-First Author,IF: 2.047, JCR: 3区)

5) Y. Liu#, S. Huang#, H. Jiang, J. Xiong, Y. Wang, M. Ou, J. Cai, C. Yang, Z. Wang, S. Ge*, N. Xia. The prevalence of latent tuberculosis infection in rural Jiangsu, China [J]. Public Health, 2017, 146: 39-45. (Co-First Author,IF: 1.696, JCR: 4区)

6) Feng-Cai Zhu#, Shou-Jie Huang#, Ting Wu, Xue-Feng Zhang, Zhong-Ze Wang, Xing Ai, Qiang Yan, Chang-Lin Yang, Jia-Ping Cai, Han-Min Jiang, Yi-Jun Wang, Mun-Hon Ng, Jun Zhang*, Ning-Shao Xia. Epidemiology of Zoonotic Hepatitis E: A Community-Based Surveillance Study in a Rural Population in China [J]. PloS one, 2014, 9(1): e87154. (Co-First Author, IF: 2.776, JCR: 3区)

7) Yuemei Hu#, Shou-Jie Huang#, Kai Chu, Ting Wu, Zhong-Ze Wang, Chang-Lin Yang, Jia-Ping Cai, Han-Min Jiang, Yi-Jun Wang, Meng Guo, Xiao-Hui Liu, Hong-Jiang Huang, Feng-Cai Zhu, Jun Zhang*, Ning-Shao Xia. Safety of an Escherichia coli-expressed bivalent human papillomavirus (types 16 and 18) L1 virus-like particle vaccine: An open-label phase I clinical trial [J]. Human vaccines & immunotherapeutics, 2014, 10(2): 469-475. (Co-First Author, IF: 2.592, JCR: 3区)

8) Shoujie Huang#, Xuefeng Zhang#, Hanmin Jiang, Qiang Yan, Xing Ai, Yijun Wang, Jiaping Cai, Lang Jiang, Ting Wu, Zhongze Wang, Li Guan, J. Wai Kuo Shih, Mun-Hon Ng, Fengcai Zhu, Jun Zhang*, Ningshao Xia. Profile of acute infectious markers in sporadic hepatitis E [J]. PloS one, 2010, 5(10): e13560. (Co-First Author, IF: 2.776, JCR: 3区)

9) 余小娟, 潘莉莉, 苏迎盈, 吴婷, 黄守杰*. 乙戊型肝炎病毒重叠感染的研究进展[J]. 病毒学报, 2019, 35(2): 318-322. (通讯)

10) 郑亚, 李亚飞, 姚星妹, 吴婷, 黄守杰, 张军, 夏宁邵. 戊型肝炎疫苗临床研究进展[J]. 病毒学报, 2018, 34(6): 951-958. (通讯)

11) 姜汉民,王一军,张雪峰,王忠泽,杨昌林,蔡加平,闫强,吴婷,张军,朱凤才,夏宁邵,黄守杰*. 江苏省东台市农村地区散发戊型病毒性肝炎流行病学特征分析[J]. 中国人兽共患病学报, 2016, 32(1): 95-98. (通讯)

12) 姜汉民,王一军,张雪峰,陈林,王忠泽,杨昌林,蔡加平,盛炜,郑亚,黄守杰*. 血清标本保存温度和时间对ALT测定的影响[J]. 江苏预防医学, 2015 , 26 (6) :114-115. (通讯)

13) 黄守杰, 张雪峰, 黄鸿江, 姜汉民, 王一军, 蔡加平, 杨昌林, 王忠泽, 吴婷, 朱凤才, 张军, 夏宁邵. 散发型戊型肝炎与急性乙肝临床特征比较[J]. 中国人兽共患病学报, 2011, 27(1): 11-13.

合作论文

14) Jun Zhang, Xue-Feng Zhang, Shou-Jie Huang, Ting Wu, Yue-Mei Hu, Zhong-Ze Wang, Hua Wang, Han-Min Jiang, Yi-Jun Wang, Qiang Yan, Meng Guo, Xiao-Hui Liu, Jing-Xin Li, Chang-Lin Yang, Quan Tang, Ren-Jie Jiang, Hui-Rong Pan, Yi-Min Li, J. Wai-Kuo Shih, Mun-Hon Ng, Feng-Cai Zhu, Ning-Shao Xia. Long-term efficacy of a hepatitis E vaccine [J]. New England Journal of Medicine, 2015, 372(10): 914-922. (IF: 70.67, JCR: 1区)

15) Feng-Cai Zhu, Jun Zhang, Xue-Feng Zhang, Cheng Zhou, Zhong-Ze Wang, Shou-Jie Huang, Hua Wang, Chang-Lin Yang, Han-Min Jiang, Jia-Ping Cai, Yi-Jun Wang, Xing Ai, Yue-Mei Hu, Quan Tang, Xin Yao, Qiang Yan, Yang-Ling Xian, Ting Wu, Yi-Min Li, Ji Miao, Mun-Hon Ng, James Wai-Kuo Shih, Ning-Shao Xia. Efficacy and safety of a recombinant hepatitis E vaccine in healthy adults: a large-scale, randomised, double-blind placebo-controlled, phase 3 trial [J]. Lancet, 2010, 376(9744): 895-902. (IF: 59.102, JCR: 1区)

16) Ting Wu, Feng-Cai Zhu, Shou-Jie Huang, Xue-Feng Zhang, Zhong-Ze Wang, Jun Zhang, Ning-Shao Xia. Safety of hepatitis E vaccine for pregnant women: a preliminary analysis [J]. Hepatology, 2012, 55(6): 2038-2038. (IF: 14.971, JCR: 1区)

17) You-Lin Qiao#*, Ting Wu#, Rong-Cheng Li#, Yue-Mei Hu#, Li-Hui Wei#, Chang-Gui Li#, Wen Chen#, Shou-Jie Huang, Fang-Hui Zhao, Ming-Qiang Li, Qin-Jing Pan, Xun Zhang, Qing Li, Ying Hong, Chao Zhao, Wen-Hua Zhang, Yan-Ping Li, Kai Chu, Mei Li, Yun-Fei Jiang, Juan Li, Hui Zhao, Zhi-Jie Lin, Xue-Lian Cui, Wen-Yu Liu, Cai-Hong Li, Dong-Ping Guo, Li-Dong Ke, Xin Wu, Jie Tang, Guo-Qi Gao, Ba-Yi Li, Bin Zhao, Feng-Xian Zheng, Cui-Hong Dai, Meng Guo, Jun Zhao, Ying-Ying Su, Jun-ZhiWang, Feng-Cai Zhu, Shao-Wei Li, Hui-Rong Pan, Yi-Min Li, Jun Zhang*, Ning-Shao Xia*. Efficacy, Safety, and Immunogenicity of an Escherichia coli-Produced Bivalent Human Papillomavirus Vaccine: An Interim Analysis of a Randomized Clinical Trial[J]. Journal of the National Cancer Institute, 2020, 112(2): 1-9. (IF: 10.211, JCR: 1区)

18) YueMei Hu, Meng Guo, ChangGui Li, Kai Chu, WenGang He, Jing Zhang, JianXiang Gu, Juan Li, Hui Zhao, XiangHong Wu, BiZhen Lin, ZhiJie Lin, XingMei Yao, YaFei Li, FeiXue Wei, Yue Huang, YingYing Su, FengCai Zhu, ShouJie Huang, HuiRong Pan, Ting Wu, Jun Zhang and NingShao Xia. Immunogenicity noninferiority study of 2 doses and 3 doses of an Escherichia coli-produced HPV bivalent vaccine in girls vs. 3 doses in young women[J]. Science China-Life Sciences, 2019, 6(2):1-9. (IF: 3.583, JCR: 3区)

19) Brittany L. Kmush, Huan Yu, Shoujie Huang, Xuefang Zhang, Ting Wu, Kenrad E. Nelson and Alain B. Labrique. Long-term Antibody Persistence After Hepatitis E Virus Infection and Vaccination in Dongtai, China[J]. Open Forum Infectious Diseases, 2019, 6(4): 1-8. (IF: 3.371, JCR: 3区)

20) Feixue Wei, Meng Guo, Shoujie Huang, Mingqiang Li, Xuelian Cui, Yingying Su, Xin Wu, Xinjing Ma, Ya Zheng, Yue Huang, Lin Wang, Lili Pan, Ting Wu, Jun Zhang, Ningshao Xia. Sex Differences in the Incidence and Clearance of Anogenital Human Papillomavirus Infection in Liuzhou, China: An Observational Cohort Study[J]. Clinical Infectious Diseases, 2019. (IF: 9.055, JCR: 1区)

21) Feixue Wei, Yingying Su, Xingmei Yao, Xuelian Cui, Lihong Bian, Kai Yin, Xiaojuan Yu, Chunlan Zhuang, Zhaofeng Bi, Shoujie Huang, Mingqiang Li, Ting Wu, Ningshao Xia, Jun Zhang. Sex differences in the incidence and clearance of anal human papillomavirus infection among heterosexual men and women in Liuzhou, China: An observational cohort study[J]. International journal of cancer. 2019, 145: 807-816. (IF: 6.513, JCR: 1区)

22) Feixue Wei, Mingqiang Li, Xin Wu, Kai Yin, Jian Lan, Wei Sheng, Meng Guo, Shoujie Huang, Ying Wang, Yanping Li, Rongcheng Li, Yingying Su, Ting Wu, Jun Zhang, Ningshao Xia. The prevalence and concordance of human papillomavirus infection in different anogenital sites among men and women in Liuzhou, China: A population-based study[J]. International journal of cancer, 2018, 142(6): 1244-1251. (IF: 6.513, JCR: 1区)

23) Feixue Wei, Wei Sheng, Xin Wu, Kai Yin, Jian Lan, Yue Huang, Xinjing Ma, Ya Zheng, Sijie Zhuang, Shoujie Huang, Yingying Su, Mingqiang Li, Ting Wu, Jun Zhang & Ningshao Xia. Incidence of anogenital warts in Liuzhou, south China: a comparison of data from a prospective study and from the national surveillance system[J]. Emerging Microbes & Infections, 2017, 6(1): 1-8. (IF: 6.212, JCR: 2区)

24) Feixue Wei, Kai Yin, Xin Wu, Jian Lan, Shoujie Huang, Wei Sheng, Jun Zhao, Yingying Su, Ying Wang, Yanping Li, Rongcheng Li, Jun Zhang, Mingqiang Li, Ting Wu and Ningshao Xia. Human papillomavirus prevalence and associated factors in women and men in south China: a population-based study [J]. Emerging Microbes & Infections, 2016, 5(11): 1-8. (IF: 6.212, JCR: 2区)

25) Gui-Ping Wen, Zi-Min Tang, Si-Ling Wang, Wen-Fang Ji, Wei Cai, Xu Zhang, Shou-Jie Huang, Ting Wu, Jun Zhang, Zi-Zheng Zheng, Ning-Shao Xia. Classification of human and zoonotic group hepatitis E virus (HEV) using antigen detection[J]. Appl Microbiol Biotechnol, 2017, 101(23-24): 8585-8594. (IF: 3.67, JCR: 2区)

26) J. Chen, K. Yang, M. Zhang, C. Shen, J. Chen, G. Wang, S. Huang, M. Zhang, H. Xiong, H. Chen, Y. Chen, N. Xia. Rapid identification of imported influenza viruses at Xiamen International Airport via an active surveillance program [J]. Clinical Microbiology and Infection, 2017, 24(3): 289-294. (IF: 6.425, JCR: 2区)

27) Shu Chen, Zi Zhou, Fei-Xue Wei, Shou-Jie Huang, Zhong Tan, Ya Fang, Feng-Cai Zhu, Ting Wu, Jun Zhang, Ning-Shao Xia. Modeling the long-term antibody response of a hepatitis E vaccine [J]. Vaccine, 2015, 33(33): 4124-4129. (IF: 4.76, JCR: 2区)

28) Ting Wu, Yue-Mei Hu, Juan Li, Kai Chu, Shou-Jie Huang, Hui Zhao, Zhong-Ze Wang, Chang-Lin Yang, Han-Min Jiang, Yi-Jun Wang, Zhi-Jie Lin, Hui-Rong Pan, Wei Sheng, Fei-Xue Wei, Shao-Wei Li, Ying Wang, Feng-Cai Zhu, Chang-Gui Li, Jun Zhang, Ning-Shao Xia. Immunogenicity and safety of an E. coli–produced bivalent human papillomavirus (type 16 and 18) vaccine: a randomized controlled phase 2 clinical trial [J]. Vaccine, 2015, 33(32): 3940-3946. (IF: 4.76, JCR: 2区)

29) Gui-Ping Wen, Zi-Min Tang, Fan Yang, Ke Zhang, Wen-Fang Ji, Wei Cai, Shou-Jie Huang, Ting Wu, Jun Zhang, Zi-Zheng Zheng, Ning-Shao Xia. A Valuable Antigen Detection Method for Diagnosis of Acute Hepatitis E[J]. Journal of clinical microbiology, 2015, 53(3): 782-788. (IF: 4.959, JCR: 2区)

30) Hui Zhao, Zhi-Jie Lin, Shou-Jie Huang, Juan Li, Xiao-Hui Liu, Meng Guo, Jun Zhang, Ning-Shao Xia, Hui-Rong Pan, Ting Wu, Chang-Gui Li. Correlation between ELISA and pseudovirion-based neutralisation assay for detecting antibodies against human papillomavirus acquired by natural infection or by vaccination [J]. Human Vaccines &Immunotherapeutics, 2014, 10(3): 740-746. (IF: 2.592, JCR: 3区)

31) J. Zhang, X.-F. Zhang, C. Zhou, Z.-Z. Wang, S.-J. Huang, X. Yao, Z.-L. Liang, T. Wu, J.-X. Li, Q. Yan, C.-L. Yang, H.-M. Jiang, H.-J. Huang, Y.-L. Xian, J. W.-K. Shih, M.-H. Ng, Y.-M. Li, J.-Z. Wang, F.-C. Zhu, N.-S. Xia. Protection against hepatitis E virus infection by naturally acquired and vaccine-induced immunity [J]. Clinical Microbiology and Infection, 2014, 20(6): O397-O405. (IF: 6.425, JCR: 2区)

32) Ting Wu, Shou-Jie Huang, Feng-Cai Zhu, Xue-Feng Zhang, Xing Ai, Qiang Yan, Zhong-Ze Wang, Chang-Lin Yang, Han-Min Jiang, Xiao-Hui Liu, Meng Guo, Hai-Lian Du, Mun-Hon Ng, Jun Zhang, Ningshao Xia. Immunogenicity and safety of hepatitis E vaccine in healthy hepatitis B surface antigen positive adults [J]. Human Vaccines & Immunotherapeutics, 2013, 9(11): 2474-2479. (IF: 2.592, JCR: 3区)

33) Y. Chen, Q. Zheng, K. Yang, F. Zeng, S.-Y. Lau, W. L. Wu, S. Huang, J. Zhang, H. Chen, N. Xia. Serological survey of antibodies to influenza A viruses in a group of people without a history of influenza vaccination[J]. Clinical Microbiology and Infection, 2011, 17(9):1347-1349. (IF: 6.425, JCR: 2区)

六 获奖和荣誉

1) 2019年获得厦门大学公共卫生学院养生堂奖教金;

2) 2015年获求是科技基金会杰出科技成就集体奖(排名:5);

3) 2014年获得厦门大学校庆中国银行教科辅奖教金;

4) 2012年获得厦门大学公共卫生学院养生堂奖教金;

5) 2012年获得江苏省科学技术奖一等奖(排名:9);


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国家传染病诊断试剂与疫苗工程技术研究中心(厦门大学)  地址:中国福建省厦门市翔安区翔安南路厦门大学翔安校区
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